A Mechanosensitive GPCR that Detects the Bloody Force
نویسندگان
چکیده
منابع مشابه
Mechanosensitive channel activation by diffusio-osmotic force.
For ion channel gating, the appearance of two distinct conformational states and the discrete transitions between them are essential, and therefore of crucial importance to all living organisms. We show that the physical interplay between two structural elements that are commonly present in bacterial mechanosensitive channels--namely, a charged vestibule and a hydrophobic constriction--creates ...
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ژورنال
عنوان ژورنال: Cell
سال: 2018
ISSN: 0092-8674
DOI: 10.1016/j.cell.2018.04.001